Well done,
Japanese!
In the past, producing fully functional
human organs happened only in the realm of science fiction. In the near future
the things will change. Some Japanese scientists has come up with a
“functional” miniature human liver that produces blood proteins and breaks down
drugs when transplanted into a mouse. Thus they gave birth to a rudimentary
functional human organ. The same technique can be used to grow other organs
like kidneys and pancreas.
The liver exhibits excellent
regenerative capacity; it can heal when less than 70 per cent of the organ is
damaged. While the liver’s failure due to moderate alcohol consumption can be
prevented by providing it sufficient time every year to heal, liver failure due
to hepatitis B infection can be easily avoided by getting vaccinated.
This is a path breaking study - more
exciting than any science fiction! Great achievement by the Japanese
scientists!
Don’t be surprised if in future it will
turn into a simple clinical procedure, providing a rescue for many diseases as
well as cases like disabilities.
It will help the siblings who are born
without some organs and even help to cure the disease caused by consumption of
alcohol. Hope that it reaches the clinic stores in less than a decade and help
the needy.
The technique is unlikely to produce
whole replacement livers, but could be used to grow mini-livers that supplement
a failing organ. Such transplants would not even need to be located near the
existing liver.
This is indeed a game-changing study
because these researchers have taken a giant step by providing proof-of-concept
demonstration of a “functional” miniature human liver that produced blood
proteins and the drugs broke down when transplanted into a mouse.
The technique is very novel and based on
the Nobel winning discovery. What remains to be seen, in the years to come, is
how the scientists can improve its efficiency. The government should promote
research on this front because this technique of producing functional human
organs will go a long way in curbing the "organ black market".
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